HIV Crossword
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
                                     
 
 
Down: 1) Increased rate of MI?possibly NRTI2) Minimal toxicity. One of these are usually part of combination therapy. NRTI3) H2 ANTAGONISTS, PPI INHIBITOR CAUTION as it needs acidic environment4) Bidirectional Drug Interactions, CYP450 SE: Rash Long Half Life7) prevents HIV DNA from being formed8) binds to g41 to prevent infusion injection site reactions NO DRUG INTERACTIONS LAST LINE AGENT11) Steven Johnson, Hepatoxicity NNRTI13) Prevents RNA from being incorporated in host DNA18) Anti Retroviral Therapy. Term not used anymore21) Sole Drug that doesn't need any addition NNRTIefavirenz, 2 NRTI- tenofovir, emtricitabine (EFV/TDF/FTC) Single Dose once a day therapy integrase inhibitor, Across: 5) Protease Inhibitor Inhibits CYP3A4 Increase bioavailability, works as a booster Decreases elimination, Increases efficacy6) CCR5 antagonist9) Fusion inhibit GP4110) Anemia, neutropenia NRTI12)  CCR5 ANTAGONIST Only drug that targets host enzyme Drug interactions14) Nephrotoxity NRTI15) GI Distress Dyslipedmia Drug Interactions-Fluticasone, Rifampin-inducer of 3a4 16) prevent production of mature virus17) Renal Elimination Black Box Warning: lactic acidosis, hepatic steatosis mainstay of early treatment 2 NRTIs19) Site injections20) Teratogenic in 1st trimester False Positive Drug Test NNRTI22) Raltegivir prevents integration of viral DNA into host DNA RIFAMPIN drug interaction23) Peripheral Neuropathy, Lipodystrophy, Lactic Acidosis, Pancreatitis mitochondrial DNA polymerase24) 2nd generation Used as 2nd line and replacement INhibits 2c9 and 19 NNRTI
 

 

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