Breathing Drugs Crossword
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
 
 
Down: 2) INJECTED; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children3) antimuscarinics - severe asthma that isn't tx by B2 agonist -- sometimes used in combo with inhaled B2 agonist SE: dry mouth, urinary retention4) leukotrine receptor antagonists (LTRA); selective antagonists of CysLT1 receptor -- not for acute attacks; orally active, used as add-on therapy and to lower dose of steroids -- mild asthmatic with exercise-induced bronchoconstriction SE: generally safe6) Beta-2 agonist (SABA), nonspecific binding SE: cardiac stimulation (tachycardia, palpitations, arrthymias), hypertension 7) antimuscarinics - severe asthma that isn't tx by B2 agonist -- sometimes used in combo with inhaled B2 agonist SE: dry mouth, urinary retention9) corticosteroid/LABA - formoterol is more rapid acting; used in patient with moderate to severe persistent asthma when their symptoms aren't controlled by inhaled corticosteroids alone10) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia12) INHALED; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children14) leukotrine receptor antagonists (LTRA); selective antagonists of CysLT1 receptor -- not for acute attacks; orally active, used as add-on therapy and to lower dose of steroids -- mild asthmatic with exercise-induced bronchoconstriction SE: generally safe16) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia17) methylxanthine - oral & slow onset, weak bronchodilator; enhances effects of B2 agonists -- prominent anti-inflammatory effects, cheap SE: 15mg/L = N/V, nervousness, seizures, arrthymia -- 40mg/L = seizures, hyperthermia, brain damage, hyperglycemia, hypokalemia, hypotension, death18) mast cell stabilizer - only helpful when taken prophylactically (reduce symtpoms and bronchial hyperactivity, decrease #/severity of attacks) -- inhalation of powder or aerosolized solutions - TX of antigen and exercise-induced asthma; less effective than corticosteroids SE: may cause throat irritation/cough19) B2 agonist (LABA) - long duration of action (~12 hours or more); not for acute symptoms SE: low systemic toxicity21) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia23) methylxanthine - weak bronchodilator, adenosine receptor antagonist25) ORAL; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children Across: 1) corticosteroid/LABA - no immediate effect (~30 minutes onset of action); used in patient with moderate to severe persistent asthma when their symptoms aren't controlled by inhaled corticosteroids alone5) 5-LOX inhibitor; prevents leukotriene formation -- not for acute attacks; orally active, used as add-on therapy and to lower dose of steroids -- mild asthmatic with exercise-induced bronchoconstriction SE: asthenia, HA, liver toxicity 8) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia11) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia13) mast cell stabilizer - only helpful when taken prophylactically (reduce symtpoms and bronchial hyperactivity, decrease #/severity of attacks) -- inhalation of powder or aerosolized solutions - TX of antigen and exercise-induced asthma; less effective than corticosteroids SE: may cause throat irritation/cough15) anti-IgE antibody; initially injected SC q2 weeks, folllowed by monthly injections - add on therapy for patients with moderate to severe asthma -- COSTLY SE: anaphylaxis, malignant neoplasms17) INHALED; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children20) INHALED; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children22) INJECTED; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children24) B2 agonist (SABA) - selective SE: cardiac stimulation via B1 receptors -- high dose can cause death26) ORAL; corticosteroid; for both acute attacks & prophylaxis -- effective even in patients who aren't responsive to bronchodilators ---> oropharyngeal candidiasis, hoarseness, stunted growth in children27) B2 agonist (SABA) - short-acting (onset of action 5-30 min, lasting 2-3 hours) -- TX of acute asthma & exercise-induced asthma SE: cardiac stimulation at high doses, tremor, hypokalemia28) B2 agonist (LABA) - long duration of action (~12 hours or more); not for acute symptoms SE: low systemic toxicity29) antimuscarinics - off-label for acute asthma SE: tachycardia, nausea, dry mouth, constipation, urinary retention
 

 

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